continuous erythropoietin receptor activator FDA Link

a third-generation erythropoietic beta molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia

Also Known As:

CERA (erythropoietin receptor activator); Mircera; epoetin beta pegol; methoxy polyethylene glycol-epoetin beta

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Colony-Stimulating Factors: 1607
      - Erythropoietin: 12372
        continuous erythropoietin receptor activator: 123
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1607
        Erythropoietin: 12372
        continuous erythropoietin receptor activator: 123
  - Glycoproteins: 25180
    - Colony-Stimulating Factors: 1607
      - Erythropoietin: 12372
        continuous erythropoietin receptor activator: 123
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1607
        Erythropoietin: 12372
        continuous erythropoietin receptor activator: 123
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Hematopoietic Cell Growth Factors: 13
      - Colony-Stimulating Factors: 1607
        Erythropoietin: 12372
        continuous erythropoietin receptor activator: 123
Organic Chemicals: 140
- Alcohols: 610
  - Glycols: 38
    - Ethylene Glycols: 8
      - Polyethylene Glycols: 3955
        continuous erythropoietin receptor activator: 123
Macromolecular Substances: 97
- Polymers: 13529
  - Polyethylene Glycols: 3955
    - continuous erythropoietin receptor activator: 123
Biomedical and Dental Materials
- Polymers: 13529
  - Polyethylene Glycols: 3955
    - continuous erythropoietin receptor activator: 123
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13529
      - Polyethylene Glycols: 3955
        continuous erythropoietin receptor activator: 123

Paul C Nader Selected Research

Paul C Nader Research Topics

Disease

Drug/Important Bio-Agent (IBA)